Jo Anne Simon (born 1952) is an American attorney and politician serving as a member of the New York State Assembly for the 52nd District of the New York State Assembly. She is a Democrat. The district includes portions of Brooklyn Heights, Downtown Brooklyn, Cobble Hill, Carroll Gardens, Gowanus, Park Slope, Boerum Hill and DUMBO in Brooklyn. She was a candidate for Congress in New York's newly redrawn 10th congressional district in 2022.