The Mountain Valley Conference (MVC) was an athletic conference consisting of six large high schools and four school districts from Monroe County and the Lehighton Area School District from Carbon County, Pennsylvania in the United States. It was part of District XI of the Pennsylvania Interscholastic Athletic Association (PIAA). In 2014, its teams were mostly assimilated into the 18-team league of large eastern and northeastern Pennsylvania high schools known as the Eastern Pennsylvania Conference.