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The Centre of Biological Research (Spanish: Centro de Investigaciones Biológicas) is a leading research centre in Spain, specialising in molecular genetics. It belongs to the Spanish National Research Council (CSIC). Created in 1958, the centre leads Spanish and European research in the fields of biology and biomedicine. Set up under the auspices of Nobel laureate Santiago Ramón y Cajal, its first director was Gregorio Marañon. Leading scientists associated with the centre include Mariano Barbacid.