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Lancaster (locally /ˈlæŋk(ə)stər/ LANK-(ə-)stər) is a city in Fairfield County, Ohio, in the south central part of the state. As of the 2010 census, the city population was 38,780. The city is near the Hocking River, about 33 miles (53 km) southeast of Columbus and 38 miles (61 km) southwest of Zanesville. It is the county seat of Fairfield County.